Early developmental alterations of CA1 pyramidal cells in Dravet syndrome
Dravet Syndrome (DS) is most often caused by heterozygous loss-of-function mutations in the voltage-gated sodium channel gene SCN1A (Nav1.1), resulting in severe epilepsy and neurodevelopmental impairment thought to be cause by reduced interneuron excitability.However, recent studies in mouse models poison open up and say ahh t shirt suggest that i